How you start your essay will depend on the question or title. If the question is: Why is Curley’s wife an important character in the novella Of Mice and Men?. You could answer the question.
Curley’s wife regrets the path her life has taken, and laments having missed her chance to move to Hollywood and become a movie star. To make up for her misery and loneliness, she tries to connect with other people, but finds herself thwarted at every turn.